METALLO PROTEINS AND SPECTROSCOPY: RELEVANCE FOR HUMAN HEALTH AND DISEASE

01 OCTOBER 2019 | 9 a.m. - 6 p.m.

 

Metal ions integrated in proteins/enzymes are essential for life and, in particular, play determinant functions in human health and disease. Studying their mode of action requires spectroscopic methods, such as Magnetic Resonance (Nuclear and Electronic) and Vibrational spectroscopies. The meeting will gather specialists on the role of Metals in Biology and on the application of several spectroscopies that will show how they are used to understand the molecular basis of these important components of life and their medical implications.

01 OCTOBER 2019
9 a.m. - 6 p.m.

 

Metal ions integrated in proteins/enzymes are essential for life and, in particular, play determinant functions in human health and disease. Studying their mode of action requires spectroscopic methods, such as Magnetic Resonance (Nuclear and Electronic) and Vibrational spectroscopies. The meeting will gather specialists on the role of Metals in Biology and on the application of several spectroscopies that will show how they are used to understand the molecular basis of these important components of life and their medical implications.

Program

08h00 - 09h15

Registration

09h15 - 09h30

Welcome Address:
- Professor José Fragata, Vice-Rector UNL
- Professor Miguel Teixeira, ITQB

Session 1

09h30 - 10h15

Miguel Teixeira, ITQB, The Periodic Table of Metals in Biology

Key Note Lecture I

10h15 - 11h15

David Giedroc , Indiana University, Fighting over metals: Transition metals at the host-bacterial pathogen interface

Key Note Lecture I

10h15 - 11h15

David Giedroc , Indiana University, Fighting over metals: Transition metals at the host-bacterial pathogen interface

11h15 - 11h30

Coffee Break

11h30 - 12h15

Ricardo O. Louro, ITQB, Biospectroscopy: The ultimate microscope to study biology in space and time

Key Note Lecture II

12h15 - 13h15

Hugh Barr, Gloucestershire Hospitals NHS Foundation Trust, Vibrational Spectroscopy in Cancer Diagnosis

Key Note Lecture II

12h30 - 13h15

Hugh Barr, Gloucestershire Hospitals NHS Foundation Trust, Vibrational Spectroscopy in Cancer Diagnosis

13h15 - 14h30

Lunch

Session 2

Key Note Lecture III

14h30 - 15h30

Christian Greisinger, Max Planck Institute Biophysical Chemistry, Göttingen, (Metallo-)protein aggregation and interference with it in neurodegeneration and more

Session 2

Key Note Lecture III

14h30 - 15h30

Christian Greisinger, Max Planck Institute Biophysical Chemistry, Göttingen, (Metallo-)protein aggregation and interference with it in neurodegeneration and more

15h30 - 16h00

Célia V. Romão, ITQB, Free-Label X-ray Imaging of elements: from cells to tissues

16h00 - 16h30

João B. Vicente, ITQB, Crosstalk between the ‘gasotransmitters’ H2S, NO and CO in human cystathionine beta-synthase: from time-resolved spectroscopy to human pathophysiology

16h30 - 16h45

Coffee Break

16h45 - 17h15

Lígia M. Saraiva, ITQB, Metal-based CO-releasing molecules as novel bactericides

Key Note Lecture IV

17h15 - 18h15

Martin Warren, Kent University, UK, What’s so special about vitamin B12

Key Note Lecture IV

17h15 - 18h15

Martin Warren, Kent University, UK, What’s so special about vitamin B12

Speakers’ Presentation

Professor David Giedroc

Professor Hugh Barr

Professor Christian Griesinger

Professor Martin Warren

Professor Miguel Teixeira

Doctor Lígia M. Saraiva

Doctor Ricardo Louro

Doctor Célia Romão

Doctor João Vicente

Supporting Entity: